Have an outbox: I started using an outbox during my first Cure and I haven't looked back. Most of us have a problem detaching from our stuff even if it's stuff we don't use or want. Of course there's the junk. That's easy to get rid of but man do I feel guilty when I'm getting rid of something I paid good money for, that was gifted to me by a good friend or that I inherited. That's where the outbox comes in. I use a bag but you can use a box, a spot in the closet or a little-used corner of a room. I put stuff here while I live without it (and subconsciously work through the anxiety of getting rid of it). After about a month or so, it's easier to make a rational decision about what to do with it.
Quality over quantity: My life got a lot simpler when I started to cut down on how much of any one thing I bought. For example, I have two sets of sheets. One for the wash, one for the bed. It feels good knowing that I have less to store and I don't feel guilty about buying stuff that's a little better quality because I know I'm definitely going to using it.
Make one thing in every room a priority item: Concentrate on keeping that one thing clean and the rest of the room will feel clean and eventually the clean will spread to the surrounding areas.